Research Scientist, Synthetic & Medicinal Chemistry

X-Chem, Inc. is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, the company leverages its market-leading DEL platform to discover novel small molecule leads against challenging, high-value therapeutic targets. X-Chem empowers partners to rapidly screen billions of diverse, drug-like compounds simultaneously and easily identify potent hits that exhibit desired selectivity and mode of action with attractive physicochemical properties. In-house lead optimization services enable clients to progress their compounds directly for even higher quality outputs. Our expertise in medicinal chemistry, custom synthesis and scale-up process chemistry enables us to support all aspects of drug discovery, supporting lead optimization through candidate identification. Our research scientists were responsible for over 100 patents, 17 compounds advanced to IND-enabling toxicology studies, and 7 compounds reaching Phase I or beyond.

Are you passionate about pushing the boundaries of synthetic and medicinal chemistry?  X-Chem is soon expanding in Montreal!

We are seeking talented Research Scientists eager to make an impact in drug discovery. While roles aren't open just yet, we’re actively building our candidate network for exciting positions launching soon.
•    Plan and execute multi-step syntheses
•    Advance cutting-edge drug discovery programs
•    Collaborate with a world-class team of Scientists
•    Thrive in a culture of innovation, open-mindedness, and intelligent risk-taking

Qualifications

• MSc or PhD degree in synthetic organic chemistry
• Knowledge of modern synthetic organic chemistry and the ability to plan and execute multi-step syntheses
• Knowledge and applied experience of NMR spectroscopy, LCMS and automated chromatography
• Excellent oral and written communication skills, particularly related to scientific and safety matters
• Current work authorization in Canada

The company cooperates with its customers, partners and colleagues outside Quebec for the research and development of medical products based on the identification and optimization of small molecules enabling the development of specific drugs. Interaction with colleagues and partners outside Quebec, notably in Budapest and Waltham, is constant. Consequently, knowledge of English is required for this unique and specialized position.  

Knowledge of French is required for positions permanently located in Quebec, so that the incumbent can communicate as needed with colleagues, customers and partners in Quebec. French-language training will be offered to any incumbent of a permanent position in Quebec who does not have a good knowledge of French. 

Our research scientists innovate beyond reported chemistry while focusing on delivery. We all share a passion for staying at the forefront of medicinal and synthetic chemistry. To drive innovation, we acknowledge the importance of intelligent risk-taking, open-mindedness and initiative. We encourage creativity in an informal environment and recognize everyone’s contribution as part of a team to work together toward a common vision.

What are the benefits joining us?

We are focused on the development and career progression of our people to reach their full potential through workshops, training courses and mentor guidance. X-Chem offers competitive compensation (salary and performance incentive) and interesting benefits package. Benefits we offer include: Medical, Dental, STD/LTD and Life Insurance, Retirement Plan with employer match; paid vacations starting at 3 weeks plus paid Christmas shutdown; casual dress, vision care including prescription safety glasses, training sessions and workshops, social hours and team-building company events.